i know that in tuberculosis bacteria in the lungs become isolated in small nodules called tubercles but i need more of an explanation please.
Respiratory Diseases - 1 Answers
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Tuberculosis causes fibrous connective tissue to develop around the sites of infection, forming structures called tubercles. By walling off the bacteria, the tubercles help inhibit their spread. Sometimes this protective mechanism fails, and the bacteria flourish throughout the lungs, and may even spread to other organs. As lung tissue is destroyed, the surface area for gas exchange decreases. In addition, the widespread fibrous tissue increases the thickness of the respiratory membrane, further restricting gas exchange
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